MMV-supported projects

 

MMV support to projects may include financial, in-kind, and advisory activities.

Legend

 Global Fund Expert Review Panel (ERP) reviewed product – permitted for time-limited procurement, while regulatory/WHO prequalification review is ongoing.


 Included in MMV portfolio after product approval and/or development. DNDi and partners completed development and registration of ASMQ and ASAQ. 

 WHO Prequalified OR approved/positive opinion by regulatory bodies who are ICH members/observers.  

 Paediatric formulation.

   Via a bioequivalence study.

Brand names:

1 Coartem® Dispersible

2 Artesun®

3 Larinate® 60mg

4 Eurartesim®

5 Pyramax® tablets or granules

6 ASAQ Winthrop®

7 SPAQ-COTM

8 Supyra®

9 100mg Artesunate Rectocaps

10 ArtecapTM

11 Kozenis/Krintafel (Trademarks owned or licensed by GSK) 

Target Product Profiles indicated by bars at the bottom of each coumpound box

____  3-day cure, artemisinin-based combination therapies 

____  Uncomplicated malaria treatments for single-exposure radical cure (SERC) and/ or resistance management (TPP-1)

____  Severe malaria treatment/ pre-referral intervention

____  Intermittent/ seasonal malaria chemoprevention 

____  Products targeting prevention of relapse for P. vivax 

____  Single-exposure chemoprotection (SEC) TPP-2

Target Candidate Profiles activities for each individual molecule, indicated by symbols added to compounds in the translational or product development portfolio


 Asexual blood stages


 Relapse prevention


 Transmission reduction


 Prophylaxis