Publications

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765 found

Parasite-Host Dynamics throughout Antimalarial Drug Development Stages Complicate the Translation of Parasite Clearance

18 Mar 2021
Scientific article

Novel Antimalarial Tetrazoles and Amides Active against the Hemoglobin Degradation Pathway in Plasmodium falciparum

11 Mar 2021
Scientific article

Identification and Profiling of a Novel Diazaspiro[3.4]octane Chemical Series Active against Multiple Stages of the Human Malaria Parasite Plasmodium falciparum and Optimization Efforts

25 Feb 2021
Scientific article

MAIP: a web service for predicting blood-stage malaria inhibitors

22 Feb 2021
Scientific article

Not only COVID-19: public-private partnerships delivering new drugs to fight diseases of poverty

11 Feb 2021
Advocacy article

Hepatic safety of repeated treatment with pyronaridine-artesunate versus artemether-lumefantrine in patients with uncomplicated malaria: a secondary analysis of the WANECAM 1 data from Bobo-Dioulasso, Burkina Faso

29 Jan 2021
Scientific article

Keeping the Promise: Product Development Partnerships’ Role in the New Age of Health Research and Product Development

28 Jan 2021
External publication

1-Methyl-1 H-pyrazole-5-carboxamide Derivatives Exhibit Unexpected Acute Mammalian Toxicity

14 Jan 2021
Scientific article

Pregnancy registries: a step towards better antimalarials for women

17 Dec 2020
Advocacy article

Retrospective Analysis Using Pharmacokinetic/Pharmacodynamic Modeling and Simulation Offers Improvements in Efficiency of the Design of Volunteer Infection Studies for Antimalarial Drug Development

16 Dec 2020
Scientific article

Effectiveness of seasonal malaria chemoprevention at scale in west and central Africa: an observational study

05 Dec 2020
Access article / report

World Malaria Report 2020

30 Nov 2020
External publication

World Malaria Reports

30 Nov 2020
Series

Q&A: Scaling up preventive malaria treatment in pregnancy by enhancing African manufacturing capacity

27 Nov 2020
Advocacy article

Escaping from Flatland: Antimalarial Activity of sp3-Rich Bridged Pyrrolidine Derivatives

10 Nov 2020
Scientific article

The impact of delayed treatment of uncomplicated P. falciparum malaria on progression to severe malaria: A systematic review and a pooled multicentre individual-patient meta-analysis

19 Oct 2020
Scientific article

International Day of the Girl Child: Get up, speak out and save adolescent girls from malaria

14 Oct 2020
Advocacy article

MiMBa: Combatting malaria in pregnant and breastfeeding women

23 Sep 2020
External publication

Efficacy and Safety of Pyronaridine-Artesunate for the Treatment of Uncomplicated Plasmodium falciparum and Plasmodium vivax Malaria in Myanmar

01 Sep 2020
Scientific article

Lipid Compositions in Infant Formulas Affect the Solubilization of Antimalarial Drugs Artefenomel (OZ439) and Ferroquine during Digestion

06 Jul 2020
Scientific article

MMV Rapport Annuel 2019

03 Jul 2020
MMV Annual Report

MMV Annual Report 2019

02 Jul 2020
MMV Annual Report

Plasmodium vivax liver stage assay platforms using Indian clinical isolates

22 Jun 2020
Scientific article

Discovery of Anti-Amoebic Inhibitors from Screening the MMV Pandemic Response Box on Balamuthia mandrillaris, Naegleria fowleri, and Acanthamoeba castellanii

16 Jun 2020
Scientific article

Pharmacogenetic assessment of tafenoquine efficacy in patients with Plasmodium vivax malaria

16 Jun 2020
Scientific article

First-in-human clinical trial to assess the safety, tolerability and pharmacokinetics of P218, a novel candidate for malaria chemoprotection

01 Jun 2020
Scientific article

OPT-SMC: Implementation research to optimize delivery and effectiveness of seasonal malaria chemoprevention

14 May 2020
Access article / report, External publication

A screening of the MMV Pathogen Box® reveals new potential antifungal drugs against the etiologic agents of chromoblastomycosis

13 May 2020
Pathogen Box article, Scientific article

The malaria season is coming – we must continue to protect children at risk

27 Apr 2020
External publication
Photo: Gerasimov174

Novel Endochin-Like Quinolones Exhibit Potent In Vitro Activity against Plasmodium knowlesi but Do Not Synergize with Proguanil

21 Apr 2020
Scientific article

Targeting Plasmepsins-An Achilles' Heel of the Malaria Parasite

08 Apr 2020
Scientific article

WHO's Q&A on malaria and the COVID-19 pandemic

27 Mar 2020
External publication

MiMBa: Malaria in Mothers and Babies

18 Mar 2020
Advocacy article, MMV issues in focus

An adaptable soft-mold embossing process for fabricating optically-accessible, microfeature-based culture systems and application toward liver stage antimalarial compound testing.

17 Mar 2020
Scientific article

Neurological and psychiatric safety of tafenoquine in Plasmodium vivax relapse prevention: a review

14 Mar 2020
Scientific article

Ensemble modeling highlights importance of understanding parasite-host behavior in preclinical antimalarial drug development

10 Mar 2020
Scientific article

Closing the gender gap in medical research

08 Mar 2020
External publication

Factors affecting the electrocardiographic QT interval in malaria: A systematic review and meta-analysis of individual patient data

05 Mar 2020
Scientific article

Triclabendazole for the treatment of fascioliasis

03 Feb 2020
Pathogen Box article, Scientific article

Anti‑malarial ozonides OZ439 and OZ609 tested at clinically relevant compound exposure parameters in a novel ring‑stage survival assay

18 Jan 2020
Scientific article

Antimalarial development: a step forward in the global fight against antimicrobial resistance

16 Jan 2020
Advocacy article

An in vitro toolbox to accelerate anti-malarial drug discovery and development

13 Jan 2020
Scientific article

Ivermectin as a novel complementary malaria control tool to reduce incidence and prevalence: a modelling study

13 Jan 2020
Scientific article

The IUPHAR/BPS Guide to pharmacology in 2020: extending immunopharmacology content and introducing the IUPHAR/MMV Guide to malaria pharmacology

08 Jan 2020
Scientific article

A Single-Dose Combination Study with the Experimental Antimalarials Artefenomel and DSM265 To Determine Safety and Antimalarial Activity against Blood-Stage Plasmodium falciparum in Healthy Volunteers

20 Dec 2019
Scientific article

P. vivax malaria: Transforming treatment & revitalizing elimination efforts

19 Dec 2019
MMV issues in focus

An Exclusive Computational Insight toward Molecular Mechanism of MMV007571, A Multitarget Inhibitor of Plasmodium falciparum

17 Dec 2019
Malaria Box article, Scientific article

The Development Process for Discovery and Clinical Advancement of Modern Antimalarials

12 Dec 2019
Scientific article

In vitro selection predicts malaria parasite resistance to dihydroorotate dehydrogenase inhibitors in a mouse infection model

04 Dec 2019
Scientific article

Destination eradication: we need to boost innovation to end malaria

29 Nov 2019
Advocacy article

World Malaria Report 2019

28 Nov 2019
External publication

The relative rate of kill of the MMV Malaria Box compounds provides links to the mode of antimalarial action and highlights scaffolds of medicinal chemistry interest

19 Nov 2019
Malaria Box article, Scientific article

Collaboration pushes frontiers of anti-malaria drug regimes

18 Nov 2019
External publication

The proteasome as a target for protozoan parasites

04 Nov 2019
Scientific article

In vitro activity of ferroquine against artemisinin-based combination therapy (ACT)-resistant Plasmodium falciparum isolates from Cambodia

01 Nov 2019
Scientific article

Exploring the Antiplasmodial 2‐Aminopyridines as Potential Antitrypanosomal Agents

31 Oct 2019
Pathogen Box article, Scientific article

Diaminoquinazoline MMV675968 from Pathogen Box inhibits Acinetobacter baumannii growth through targeting of dihydrofolate reductase

30 Oct 2019
Pathogen Box article, Scientific article

Turning the tide against severe malaria in Africa: where are we today?

27 Oct 2019
External publication

Multi-center screening of the Pathogen Box collection for schistosomiasis drug discovery

22 Oct 2019
Pathogen Box article, Scientific article

Repositionable Compounds with Antifungal Activity against Multidrug Resistant Candida auris Identified in the Medicines for Malaria Venture's Pathogen Box

01 Oct 2019
Pathogen Box article, Scientific article

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