Volunteer infection studies accelerate the clinical development of novel drugs against malaria

02 Mar 2022

Daubenberger C, Burrows JN

The Lancet Infectious Diseases
PMID: 35247323

Doi: 10.1016/S1473-3099(21)00722-2

Photo: Gerasimov_iStock

Abstract

Malaria-related morbidity and mortality is highest in young children and pregnant women, and WHO estimated that in 2020, 627 000 humans died of malaria, mainly from Plasmodium falciparum infections. Malaria elimination will foster economic development of affected countries and allow reallocation of around US$3·0 billion currently spent yearly for malaria control. Malaria elimination is thought to be achieved by a combination of interventions targeting the insect transmitting vector and the human host, including deployment of highly efficacious malaria drugs.

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