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507 found
Treating malaria: new drugs for a new era
12 Sep 2017
Randomised controlled trial of two sequential artemisinin-based combination therapy regimens to treat uncomplicated falciparum malaria in African children: a protocol to investigate safety, efficacy and adherence
30 Aug 2017
Developing new medicines to save lives, tackle drug resistance and help eradicate malaria
28 Aug 2017
Screening of TB Actives for Activity against Nontuberculous Mycobacteria Delivers High Hit Rates
15 Aug 2017
Mothers and children first: rethinking malaria drug development
07 Aug 2017
Antimalarial drug resistance: linking
Plasmodium falciparum
parasite biology to the clinic
04 Aug 2017
All it takes is a team. One goal keeper, two strikers and a reliable mid-field
04 Aug 2017
Malaria
03 Aug 2017
In vitro screening of the open source pathogen box identifies novel compounds with profound activities against
Neospora caninum
25 Jul 2017
Hemolytic Potential of Tafenoquine in Female Volunteers Heterozygous for Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency (G6PD Mahidol Variant) versus G6PD-Normal Volunteers
24 Jul 2017
Swiss Malaria Group Annual Report 2016
19 Jul 2017
Screening of the ‘Stasis Box’ identifies two kinase inhibitors under pharmaceutical development with activity against
Haemonchus contortus
05 Jul 2017
MMV Annual Report 2016
03 Jul 2017
Rapport de gestion 2016
03 Jul 2017
SMC forecasting platform: a tool to support SP+AQ availability
03 Jul 2017
Defeating malaria for good: planning the end game
01 Jul 2017
The Candidate Antimalarial Drug MMV665909 Causes Oxygen-Dependent mRNA Mistranslation and Synergises with Quinoline-Derived Antimalarials
26 Jun 2017
Benzoxaborole Antimalarial Agents. Part 5. Lead Optimization of Novel Amide Pyrazinyloxy Benzoxaboroles and Identification of a Preclinical Candidate
17 Jun 2017
Multiplex, DNase-free one-step reverse transcription PCR for
Plasmodium
18S rRNA and spliced gametocyte-specific mRNAs
19 May 2017
Antimalarial efficacy of MMV390048, an inhibitor of
Plasmodium
phosphatidylinositol 4-kinase
26 Apr 2017
Susceptibility Testing of Medically Important Parasites
26 Apr 2017
How Reagan beat severe malaria
25 Apr 2017
Discovery of a Novel Antifungal Agent in the Pathogen Box
12 Apr 2017
Plasmodium falciparum
K13 Mutations Differentially Impact Ozonide Susceptibility and Parasite Fitness
In Vitro
11 Apr 2017
Challenges for achieving safe and effective radical cure of
Plasmodium vivax
: a round table discussion of the APMEN Vivax Working Group
07 Apr 2017
DSM265 for
Plasmodium falciparum
chemoprophylaxis: a randomised, double blinded, phase 1 trial with controlled human malaria infection
28 Mar 2017
Safety, tolerability, pharmacokinetics, and activity of the novel long-acting antimalarial DSM265: a two-part first-in-human phase 1a/1b randomised study
28 Mar 2017
Identifying the need for new drugs – Opening doors
20 Mar 2017
Addressing challenges to antimalarial access and malaria case management
14 Mar 2017
Managing intellectual property to develop medicines for the world’s poorest
24 Feb 2017
Stereochemical Aspects of T3P Amidations
21 Feb 2017
G-Finder 2016
16 Feb 2017
Accepting the Invitation to Open Innovation in Malaria Drug Discovery: Synthesis, Biological Evaluation, and Investigation on the Structure-Activity Relationships of Benzo[b]thiophene-2-carboxamides as Antimalarial Agents
14 Feb 2017
Substrate-analogous inhibitors exert antimalarial action by targeting the
Plasmodium
lactate transporter PfFNT at nanomolar scale
08 Feb 2017
The Malaria Parasite's Lactate Transporter PfFNT Is the Target of Antiplasmodial Compounds Identified in Whole Cell Phenotypic Screens
08 Feb 2017
A novel in vitro image-based assay identifies new drug leads for giardiasis
27 Jan 2017
In vitro activity of anti-malarial ozonides against an artemisinin-resistant isolate
25 Jan 2017
New developments in anti-malarial target candidate and product profiles
13 Jan 2017
SAR of the Antimalarial Ozonide Artefenomel (OZ439)
04 Jan 2017
Safety of a fixed-dose combination of artesunate and amodiaquine for the treatment of uncomplicated
Plasmodium falciparum
malaria in real-life conditions of use in Côte d’Ivoire
03 Jan 2017
How to tackle antimalarial resistance?
27 Dec 2016
Control and Elimination of
Plasmodium vivax
Malaria: The Evidence Base
22 Dec 2016
World Malaria Report 2016
13 Dec 2016
Novel inhibitors of
Plasmodium falciparum
based on 2,5-disubstituted furans
11 Dec 2016
Identification of inhibitors that dually target the new permeability pathway and dihydroorotate dehydrogenase in the blood stage of
Plasmodium falciparum
22 Nov 2016
Parasitological Clearance Rates and Drug Concentrations of a Fixed Dose Combination of Azithromycin-Chloroquine in Asymptomatic Pregnant Women with
Plasmodium Falciparum
Parasitemia: An Open-Label, Non-Comparative Study in Sub- Saharan Africa
18 Nov 2016
Putting children and mothers first
16 Nov 2016
MMV at a Glance
31 Oct 2016
The role of intellectual property in the battle against malaria
28 Oct 2016
Screening the Pathogen Box for Identification of Candida albicans Biofilm Inhibitors
24 Oct 2016
Metabolomics-based screening of the Malaria Box reveals both novel and established mechanisms of action
21 Oct 2016
Metabolomic Profiling of the Malaria Box Reveals Antimalarial Target Pathways
21 Oct 2016
Comparison of artesunate–mefloquine and artemether–lumefantrine fixed-dose combinations for treatment of uncomplicated Plasmodium falciparum malaria in children younger than 5 years in sub-Saharan Africa: a randomised, multicentre, phase 4 trial
20 Oct 2016
Identification of a Potential Antimalarial Drug Candidate from a Series of 2‑Aminopyrazines by Optimization of Aqueous Solubility and Potency across the Parasite Life Cycle
17 Oct 2016
Diagnosis and Treatment of
Plasmodium vivax
Malaria
05 Oct 2016
Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose–Efficacy Modeling
04 Oct 2016
Pharmacokinetic Interactions between Tafenoquine and Dihydroartemisinin-piperaquine or Artemether-lumefantrine in Healthy Adult Subjects
03 Oct 2016
Discovery of a Quinoline-4-carboxamide Derivative with a Novel Mechanism of Action, Multistage Antimalarial Activity, and Potent in Vivo Efficacy
28 Sep 2016
A Triazolopyrimidine-Based Dihydroorotate Dehydrogenase Inhibitor with Improved Drug-like Properties for Treatment and Prevention of Malaria
17 Sep 2016
Open Source Drug Discovery: Highly Potent Antimalarial Compounds Derived from the Tres Cantos Arylpyrroles
14 Sep 2016
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