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Adam Aspinall
André-Marie Tchouatieu
Benoit Laleu
Brice Campo
Cristina Donini
David Reddy
Didier Leroy
Elizabeth Poll
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Fiona Macintyre
George Jagoe
Hanu Ramachandruni
Helen Demarest
Isabelle Borghini-Fuhrer
James Duffy
Jaya Banerji
Jeremy Burrows
Jörg Möhrle
Maud Majeres Lugand
Mélanie Rouillier
Nada Abla Geiser
Nada Araeipour
Nathalie Gobeau
Nicole Andenmatten
Paul Willis
Pierre Hugo
Silvia Ferazzi
Stephan Duparc
Stephan Chalon
Sylvie Fonteilles-Drabek
Tim Wells
Wiweka Kaszubska

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Publications

Saving two lives, not just one: medicines for malaria during pregnancy

Solving market failure while saving children’s lives – the case of malaria

MalaFA (Malaria Futures for Asia)

The life-saving benefits of pre-referral management

Are fake drugs hampering the fight against malaria?

African isolates show a high proportion of multiple copies of the Plasmodium falciparum plasmepsin-2 gene, a piperaquine resistance marker

Plasmodium knowlesi exhibits distinct in vitro drug susceptibility profiles from those of Plasmodium falciparum

Caenorhabditis elegans Infrared-Based Motility Assay Identified New Hits for Nematicide Drug Development

Oral combination therapy for malaria: Ferroquine affects the solubilisation of OZ439 during in vitro lipolysis in milk

Spray drying OZ439 nanoparticles to form stable, water-dispersible powders for oral malaria therapy

Healthy nations, sustainable economies: How innovation can better ensure health for all

Leveraging the Medicines for Malaria Venture malaria and pathogen boxes to discover chemical inhibitors of East Coast fever

Children and malaria: treating and protecting the most vulnerable

MMV at a Glance

Why we must prioritize malaria treatment for children

G-Finder 2018

Effects of Dihydroartemisinin-Piperaquine Phosphate and Artemether-Lumefantrine on QTc Interval Prolongation

Evaluation of the effects on the QT interval of 4 artemisinin-based combination therapies for the treatment of uncomplicated malaria by use of a correction-free and heart rate-free method

Single-Dose Tafenoquine to Prevent Relapse of Plasmodium vivax Malaria

Tafenoquine versus Primaquine to Prevent Relapse of Plasmodium vivax Malaria

Diverse Chemical Compounds Target Plasmodium falciparum Plasma Membrane Lipid Homeostasis

Improved access to early diagnosis and complete treatment of malaria in Odisha, India

Connecting the dots between early childhood development, health systems and innovation to unleash future potential

Open-source discovery of chemical leads for next-generation chemoprotective antimalarials

World Malaria Report 2018

Early Antischistosomal Leads Identified from in Vitro and in Vivo Screening of the Medicines for Malaria Venture Pathogen Box

Injectable anti-malarials revisited: discovery and development of new agents to protect against malaria

Medicine for malaria: setbacks and successes on the road to eradication

Repurposing of an old drug: In vitro and in vivo efficacies of buparvaquone against Echinococcus multilocularis

Working to Stop Malaria Relapse for Good

Screening of the Pathogen Box reveals new starting points for anti-trypanosomal drug discovery

Developing next-generation tools to stop malaria relapse

Identification of Anti-staphylococcal and Anti-biofilm Compounds by Repurposing the Medicines for Malaria Venture Pathogen Box

Diurnal variation in expired breath volatiles in malaria-infected and healthy volunteers

Using Human Plasma as an Assay Medium in Caco-2 Studies Improves Mass Balance for Lipophilic Compounds

Population Pharmacokinetics of Tafenoquine, a Novel Anti-Malarial

In-silico screening of small molecule inhibitors against Lactate Dehydrogenase (LDH) of Cryptosporidium parvum

Screening the Pathogen Box against Plasmodium sexual stages using a new nanoluciferase based transgenic line of P. bergheiidentifies transmission-blocking compounds

Screening of the Pathogen Box for inhibitors with dual efficacy against Giardia lamblia and Cryptosporidium parvum

A Flow Cytometry Method for Dissecting the Cell Differentiation Process of Entamoeba Encystation

The effect of chloroquine dose and primaquine on Plasmodium vivax recurrence: a WorldWide Antimalarial Resistance Network systematic review and individual patient pooled meta-analysis

Development of NanoLuc-PEST expressing Leishmania mexicana as a new drug discovery tool for axenic- and intramacrophage-based assays

MMV Annual Report 2017

2,3,8-Trisubstituted Quinolines with Antimalarial Activity

Evaluating New Compounds to Treat Burkholderia pseudomallei Infections

Interactions of Artefenomel (OZ439) with Milk during Digestion: Insights into Digestion-Driven Solubilization and Polymorphic Transformations

Bridging the gaps in malaria R&D: An analysis of funding—from basic research and product development to research for implementation

Antimalarial activity of single-dose DSM265, a novel plasmodium dihydroorotate dehydrogenase inhibitor in patients with uncomplicated Plasmodium falciparum or Plasmodium vivax malaria infection: a proof-of-concept, open-label, phase 2a study

Identification, Characterization, and Optimization of 2,8-Disubstituted-1,5-naphthyridines as Novel Plasmodium falciparum Phosphatidylinositol-4-kinase Inhibitors with in Vivo Efficacy in a Humanized Mouse Model of Malaria

Diverse antimalarials from whole-cell phenotypic screens disrupt malaria parasite ion and volume homeostasis

Rapport de gestion 2017

Application of the Stable Isotope Label Approach in Clinical Development-Supporting Dissolution Specifications for a Commercial Tablet Product with Tafenoquine, a Long Half-life Compound

Every Child, Everywhere: Leveraging Innovation for Child-friendly Medicines for Poverty-related and Neglected Tropical Diseases

Predicting transmission blocking potential of anti-malarial compounds in the Mosquito Feeding Assay using Plasmodium falciparum Male Gamete Inhibition Assay

Screening a repurposing library, the Medicines for Malaria Venture Stasis Box, against Schistosoma mansoni

Pathogen Box screening for hit identification against Mycobacterium abscessus

Addressing the most neglected diseases through an open research model: The discovery of fenarimols as novel drug candidates for eumycetoma

Safety Experience During Real-World Use of Injectable Artesunate in Public Health Facilities in Ghana and Uganda: Outcomes of a Modified Cohort Event Monitoring Study (CEMISA)

Combating malaria

Malaria progress has levelled but new drugs are due

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