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Series
486 found
Multiplex, DNase-free one-step reverse transcription PCR for
Plasmodium
18S rRNA and spliced gametocyte-specific mRNAs
19 May 2017
Antimalarial efficacy of MMV390048, an inhibitor of
Plasmodium
phosphatidylinositol 4-kinase
26 Apr 2017
Susceptibility Testing of Medically Important Parasites
26 Apr 2017
How Reagan beat severe malaria
25 Apr 2017
Discovery of a Novel Antifungal Agent in the Pathogen Box
12 Apr 2017
Challenges for achieving safe and effective radical cure of
Plasmodium vivax
: a round table discussion of the APMEN Vivax Working Group
07 Apr 2017
DSM265 for
Plasmodium falciparum
chemoprophylaxis: a randomised, double blinded, phase 1 trial with controlled human malaria infection
28 Mar 2017
Safety, tolerability, pharmacokinetics, and activity of the novel long-acting antimalarial DSM265: a two-part first-in-human phase 1a/1b randomised study
28 Mar 2017
Identifying the need for new drugs – Opening doors
20 Mar 2017
Addressing challenges to antimalarial access and malaria case management
14 Mar 2017
Managing intellectual property to develop medicines for the world’s poorest
24 Feb 2017
G-Finder 2016
16 Feb 2017
Accepting the Invitation to Open Innovation in Malaria Drug Discovery: Synthesis, Biological Evaluation, and Investigation on the Structure-Activity Relationships of Benzo[b]thiophene-2-carboxamides as Antimalarial Agents
14 Feb 2017
Substrate-analogous inhibitors exert antimalarial action by targeting the
Plasmodium
lactate transporter PfFNT at nanomolar scale
08 Feb 2017
The Malaria Parasite's Lactate Transporter PfFNT Is the Target of Antiplasmodial Compounds Identified in Whole Cell Phenotypic Screens
08 Feb 2017
A novel in vitro image-based assay identifies new drug leads for giardiasis
27 Jan 2017
In vitro activity of anti-malarial ozonides against an artemisinin-resistant isolate
25 Jan 2017
New developments in anti-malarial target candidate and product profiles
13 Jan 2017
SAR of the Antimalarial Ozonide Artefenomel (OZ439)
04 Jan 2017
Safety of a fixed-dose combination of artesunate and amodiaquine for the treatment of uncomplicated
Plasmodium falciparum
malaria in real-life conditions of use in Côte d’Ivoire
03 Jan 2017
How to tackle antimalarial resistance?
27 Dec 2016
Control and Elimination of
Plasmodium vivax
Malaria: The Evidence Base
22 Dec 2016
World Malaria Report 2016
13 Dec 2016
Novel inhibitors of
Plasmodium falciparum
based on 2,5-disubstituted furans
11 Dec 2016
Identification of inhibitors that dually target the new permeability pathway and dihydroorotate dehydrogenase in the blood stage of
Plasmodium falciparum
22 Nov 2016
Parasitological Clearance Rates and Drug Concentrations of a Fixed Dose Combination of Azithromycin-Chloroquine in Asymptomatic Pregnant Women with
Plasmodium Falciparum
Parasitemia: An Open-Label, Non-Comparative Study in Sub- Saharan Africa
18 Nov 2016
Putting children and mothers first
16 Nov 2016
MMV at a Glance
31 Oct 2016
The role of intellectual property in the battle against malaria
28 Oct 2016
Screening the Pathogen Box for Identification of Candida albicans Biofilm Inhibitors
24 Oct 2016
Metabolomics-based screening of the Malaria Box reveals both novel and established mechanisms of action
21 Oct 2016
Metabolomic Profiling of the Malaria Box Reveals Antimalarial Target Pathways
21 Oct 2016
Identification of a Potential Antimalarial Drug Candidate from a Series of 2‑Aminopyrazines by Optimization of Aqueous Solubility and Potency across the Parasite Life Cycle
17 Oct 2016
Diagnosis and Treatment of
Plasmodium vivax
Malaria
05 Oct 2016
Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose–Efficacy Modeling
04 Oct 2016
Pharmacokinetic Interactions between Tafenoquine and Dihydroartemisinin-piperaquine or Artemether-lumefantrine in Healthy Adult Subjects
03 Oct 2016
Discovery of a Quinoline-4-carboxamide Derivative with a Novel Mechanism of Action, Multistage Antimalarial Activity, and Potent in Vivo Efficacy
28 Sep 2016
A Triazolopyrimidine-Based Dihydroorotate Dehydrogenase Inhibitor with Improved Drug-like Properties for Treatment and Prevention of Malaria
17 Sep 2016
Open Source Drug Discovery: Highly Potent Antimalarial Compounds Derived from the Tres Cantos Arylpyrroles
14 Sep 2016
A Phase II pilot trial to evaluate safety and efficacy of ferroquine against early
Plasmodium falciparum
in an induced blood stage malaria infection study
13 Sep 2016
Defining the Effectiveness of Antimalarial Chemotherapy: Investigation of the Lag in Parasite Clearance Following Drug Administration
01 Sep 2016
Metabolomic Profiling of the Malaria Box Reveals Antimalarial Target Pathways
29 Aug 2016
Open data in drug discovery and development: lessons from malaria
12 Aug 2016
Hit-to-lead studies for the antimalarial tetrahydroisoquinolone carboxanilides
09 Aug 2016
Screening of the ‘Pathogen Box’ identifies an approved pesticide with major anthelmintic activity against the barber's pole worm
28 Jul 2016
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond
28 Jul 2016
Design, synthesis and biological evaluation of 6-aryl-1,6-dihydro-1,3,5-triazine-2,4-diamines as antiplasmodial antifolates
25 Jul 2016
Single-Dose Primaquine in a Preclinical Model of Glucose-6-Phosphate Dehydrogenase Deficiency: Implications for Use in Malaria Transmission-Blocking Programs
25 Jul 2016
Extensive shared chemosensitivity between malaria and babesiosis blood-stage parasites
22 Jul 2016
Supporting research in neglected tropical diseases - Lessons from AbbVie’s neglected diseases initiative
19 Jul 2016
Annual Report 2015
28 Jun 2016
WHO malaria terminology
24 Jun 2016
Efficacy and Safety of Azithromycin-Chloroquine versus Sulfadoxine-Pyrimethamine for Intermittent Preventive Treatment of Plasmodium falciparum Malaria Infection in Pregnant Women in Africa: An Open-Label, Randomized Trial
21 Jun 2016
Trisubstituted Pyrimidines as Efficacious and Fast-Acting Antimalarials
17 Jun 2016
Efficacy of OZ439 (artefenomel) against early Plasmodium falciparum blood-stage malaria infection in healthy volunteers
05 Jun 2016
Rectal artesunate stakeholders' meeting report
25 May 2016
Gametocyte carriage in uncomplicated
Plasmodium falciparum
malaria following treatment with artemisinin combination therapy: a systematic review and meta-analysis of individual patient data
24 May 2016
GHTC briefing papers
23 May 2016
Discovering new transmission-blocking antimalarial compounds: Challenges and opportunities
18 May 2016
Lead Structure Discovery for Neglected Diseases: Product Development Partnerships Driving Drug Discovery
13 May 2016
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