Publications

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574 found

Using Human Plasma as an Assay Medium in Caco-2 Studies Improves Mass Balance for Lipophilic Compounds

17 Sep 2018
Scientific article

Population Pharmacokinetics of Tafenoquine, a Novel Anti-Malarial

10 Sep 2018
Scientific article

In-silico screening of small molecule inhibitors against Lactate Dehydrogenase (LDH) of Cryptosporidium parvum

08 Sep 2018
Pathogen Box article, Scientific article

Screening the Pathogen Box against Plasmodium sexual stages using a new nanoluciferase based transgenic line of P. bergheiidentifies transmission-blocking compounds

04 Sep 2018
Pathogen Box article, Scientific article

Screening of the Pathogen Box for inhibitors with dual efficacy against Giardia lamblia and Cryptosporidium parvum

06 Aug 2018
Pathogen Box article, Scientific article

A Flow Cytometry Method for Dissecting the Cell Differentiation Process of Entamoeba Encystation

24 Jul 2018
Pathogen Box article, Scientific article

The effect of chloroquine dose and primaquine on Plasmodium vivax recurrence: a WorldWide Antimalarial Resistance Network systematic review and individual patient pooled meta-analysis

19 Jul 2018
Scientific article

Development of NanoLuc-PEST expressing Leishmania mexicana as a new drug discovery tool for axenic- and intramacrophage-based assays

12 Jul 2018
Pathogen Box article, Scientific article

MMV Annual Report 2017

09 Jul 2018
MMV Annual Report

2,3,8-Trisubstituted Quinolines with Antimalarial Activity

04 Jul 2018
Scientific article

Evaluating New Compounds to Treat Burkholderia pseudomallei Infections

25 Jun 2018
Pathogen Box article, Scientific article

Bridging the gaps in malaria R&D: An analysis of funding—from basic research and product development to research for implementation

19 Jun 2018
External publication, Financing / policy report

Antimalarial activity of single-dose DSM265, a novel plasmodium dihydroorotate dehydrogenase inhibitor in patients with uncomplicated Plasmodium falciparum or Plasmodium vivax malaria infection: a proof-of-concept, open-label, phase 2a study

13 Jun 2018
Scientific article

Identification, Characterization, and Optimization of 2,8-Disubstituted-1,5-naphthyridines as Novel Plasmodium falciparum Phosphatidylinositol-4-kinase Inhibitors with in Vivo Efficacy in a Humanized Mouse Model of Malaria

11 Jun 2018
Pathogen Box article, Scientific article

Diverse antimalarials from whole-cell phenotypic screens disrupt malaria parasite ion and volume homeostasis

11 Jun 2018
Pathogen Box article, Scientific article

Rapport de gestion 2017

06 Jun 2018
MMV Annual Report

Application of the Stable Isotope Label Approach in Clinical Development-Supporting Dissolution Specifications for a Commercial Tablet Product with Tafenoquine, a Long Half-life Compound

04 Jun 2018
Scientific article

Predicting transmission blocking potential of anti-malarial compounds in the Mosquito Feeding Assay using Plasmodium falciparum Male Gamete Inhibition Assay

17 May 2018
Scientific article

Screening a repurposing library, the Medicines for Malaria Venture Stasis Box, against Schistosoma mansoni

15 May 2018
Scientific article

Pathogen Box screening for hit identification against Mycobacterium abscessus

26 Apr 2018
Pathogen Box article, Scientific article

Addressing the most neglected diseases through an open research model: The discovery of fenarimols as novel drug candidates for eumycetoma

26 Apr 2018
Pathogen Box article, Scientific article

Combating malaria

25 Apr 2018
Advocacy article

Malaria progress has levelled but new drugs are due

25 Apr 2018
Advocacy article

Preparing the ground in the Brazilian Amazon for a new antimalarial to reduce relapse

25 Apr 2018
Advocacy article

Safety Experience During Real-World Use of Injectable Artesunate in Public Health Facilities in Ghana and Uganda: Outcomes of a Modified Cohort Event Monitoring Study (CEMISA)

25 Apr 2018
Access article / report, Scientific article

An automated high-throughput system for phenotypic screening of chemical libraries on C. elegans and parasitic nematodes

18 Apr 2018
Pathogen Box article, Scientific article

Identification of Fast-Acting 2,6-Disubstituted Imidazopyridines That Are Efficacious in the in Vivo Humanized Plasmodium falciparum NODscidIL2Rγnull Mouse Model of Malaria

17 Apr 2018
Scientific article

Investigating a second valley of death in malaria R&D

16 Apr 2018
External publication

Defeating Malaria: Innovative Partnerships, Innovative Treatment

05 Apr 2018
Advocacy article

The Curious Case of the OZ439 Mesylate Salt: An Amphiphilic Antimalarial Drug with Diverse Solution and Solid State Structures

30 Mar 2018
Scientific article

Pyronaridine–artesunate or dihydroartemisinin–piperaquine versus current first-line therapies for repeated treatment of uncomplicated malaria: a randomised, multicentre, open-label, longitudinal, controlled, phase 3b/4 trial

29 Mar 2018
Scientific article

Targeting Channels and Transporters in Protozoan Parasite Infections

27 Mar 2018
Pathogen Box article, Scientific article

Encapsulation of OZ439 into Nanoparticles for Supersaturated Drug Release in Oral Malaria Therapy

26 Mar 2018
Scientific article

Sustainable Development Goals: Delivering Change

22 Mar 2018
External publication

Multiple-level stakeholder engagement in malaria clinical trials: addressing the challenges of conducting clinical research in resource-limited settings

22 Mar 2018
Scientific article

High-Content Screening of the Medicines for Malaria Venture Pathogen Box for Plasmodium falciparum Digestive Vacuole-Disrupting Molecules Reveals Valuable Starting Points for Drug Discovery

23 Feb 2018
Pathogen Box article, Scientific article

Potent Plasmodium falciparum gametocytocidal compounds identified by exploring the kinase inhibitor chemical space for dual active antimalarials

06 Feb 2018
Scientific article

MMV's 2018 Advertorial

31 Jan 2018
MMV general

Seasonal malaria chemoprevention: how to sustain the impact in Africa's sub-Sahel region?

30 Jan 2018
Access article / report, Advocacy article

Targeted Phenotypic Screening in Plasmodium falciparum and Toxoplasma gondii Reveals Novel Modes of Action of Medicines for Malaria Venture Malaria Box Molecules

17 Jan 2018
Malaria Box article, Scientific article

Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics

12 Jan 2018
Scientific article

Efficacy and safety of fosmidomycin-piperaquine as non-artemisinin-based combination therapy for uncomplicated falciparum malaria - A single-arm, age-de-escalation proof of concept study in Gabon

26 Dec 2017
Scientific article

G-Finder Reports

15 Dec 2017
Series

Modelling mosquito infection at natural parasite densities identifies drugs targeting

15 Dec 2017
Scientific article

G-Finder 2017

15 Dec 2017
Financing / policy report

Sustained Effectiveness of a Fixed-Dose Combination of Artesunate and Amodiaquine in 480 Patients with Uncomplicated Plasmodium falciparum Malaria in Côte d’Ivoire

07 Dec 2017
Scientific article

malERA: An updated research agenda for malaria elimination and eradication

30 Nov 2017
Scientific article

World Malaria Report 2017

29 Nov 2017
External publication

World Malaria Reports

29 Nov 2017
Series

Improved safety margin for embryotoxicity in rats for the new endoperoxide artefenomel (OZ439) as compared to artesunate

28 Nov 2017
Scientific article

A study on the public health and socioeconomic impact of substandard and falsified medical products

28 Nov 2017
External publication

WHO Global surveillance and monitoring system for substandard and falsified medical products

28 Nov 2017
External publication

Long-Lasting and Fast-Acting in Vivo Efficacious Antiplasmodial Azepanylcarbazole Amino Alcohol

28 Nov 2017
Scientific article

Discovery of new inhibitors of Toxoplasma gondii thanks to the Pathogen Box

13 Nov 2017
Pathogen Box article, Scientific article

MMV at a Glance

01 Nov 2017
MMV general

MMV Business Plan 2017–21

16 Oct 2017
MMV general

A randomised, double-blind clinical phase II trial of the efficacy, safety, tolerability and pharmacokinetics of a single dose combination treatment with artefenomel and piperaquine in adults and children with uncomplicated Plasmodium falciparum malaria

09 Oct 2017
Scientific article

Increasing uptake of rectal artesunate to buy time against severe malaria

27 Sep 2017
Access article / report

Evaluation of the pharmacokinetic-pharmacodynamic relationship of praziquantel in the Schistosoma mansoni mouse model

21 Sep 2017
Scientific article

Treating malaria: new drugs for a new era

12 Sep 2017
Scientific article

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