Optimized pyridazinone nutrient channel inhibitors are potent and specific antimalarial leads 7 July 2022 Molecular pharmacology
Clinical and population-based study design considerations to accelerate the investigation of new antiretrovirals during pregnancy 1 July 2022 Journal of the International AIDS Society
Implementation and continued validation of the malaria Plasmodium falciparum lactate dehydrogenase-based colorimetric assay for use in antiplasmodial drug screening 1 July 2022 Analytical biochemistry
Stakeholder perceptions on the deployment of multiple first-line therapies for uncomplicated malaria: a qualitative study in the health district of Kaya, Burkina Faso 27 June 2022
Parasite Viability as a Measure of In Vivo Drug Activity in Preclinical and Early Clinical Antimalarial Drug Assessment 21 June 2022
Reaction hijacking of tyrosine tRNA synthetase as a new whole-of-life-cycle antimalarial strategy 3 June 2022
Molnupiravir combined with different repurposed drugs further inhibits SARS-CoV-2 infection in human nasal epithelium in vitro 31 May 2022 Biomed Pharmacother
Effectiveness of pyronaridine-artesunate against Plasmodium malariae, Plasmodium ovale spp, and mixed-Plasmodium infections: a post-hoc analysis of the CANTAM-Pyramax trial 30 May 2022 The Lancet. Microbe
Attitudes, practices, and determinants of community care-seeking behaviours for fever/malaria episodes in the context of the implementation of multiple first-line therapies for uncomplicated malaria in the health district of Kaya, Burkina Faso 30 May 2022
An innovative study design with intermittent dosing to generate a GLP-regulatory package in preclinical species for long lasting molecule M5717, inhibitor of Plasmodium eukaryotic translation elongation factor 2 15 May 2022 Toxicology and applied pharmacology
Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183 20 April 2022
Malarial PI4K inhibitor induced diaphragmatic hernias in rat: Potential link with mammalian kinase inhibition 13 April 2022
The Pandemic Response Box─Accelerating Drug Discovery Efforts after Disease Outbreaks 7 April 2022 ACS Infect Dis
Double drugging of prolyl-tRNA synthetase provides a new paradigm for anti-infective drug development 25 March 2022
Temporal distribution of Plasmodium falciparum recrudescence following artemisinin-based combination therapy: an individual participant data meta-analysis 24 March 2022
Discovery and Preclinical Pharmacology of INE963, a Potent and Fast-Acting Blood-Stage Antimalarial with a High Barrier to Resistance and Potential for Single-Dose Cures in Uncomplicated Malaria 10 March 2022
Haematological consequences of acute uncomplicated falciparum malaria: a WorldWide Antimalarial Resistance Network pooled analysis of individual patient data 7 March 2022
Safety, pharmacokinetics, and antimalarial activity of the novel triaminopyrimidine ZY-19489: a first-in-human, randomised, placebo-controlled, double-blind, single ascending dose study, pilot food-effect study, and volunteer infection study 2 March 2022
Volunteer infection studies accelerate the clinical development of novel drugs against malaria 2 March 2022
Redoubling efforts to sustain seasonal malaria chemoprevention 28 February 2022 Lancet Child Adolesc Health