Assessment of the drugability of initial malaria infection through miniaturized sporozoite assays and high-throughput screening 23 February 2023 Commun Biol
Characterizing the blood stage antimalarial activity of tafenoquine in healthy volunteers experimentally infected with Plasmodium falciparum 16 February 2023 Clinical Infectious Diseases
Fast-Killing Tyrosine Amide ((S)-SW228703) with Blood- and Liver-Stage Antimalarial Activity Associated with the Cyclic Amine Resistance Locus (PfCARL) 10 February 2023
The Parasite Reduction Ratio (PRR) Assay Version 2: Standardized Assessment of Viability after Antimalarial Treatment In Vitro 22 January 2023 Pharmaceuticals (Basel)
Efficacy, Safety, Tolerability, and Pharmacokinetics of MMV390048 in Acute Uncomplicated Malaria 10 January 2023 Am J Trop Med Hyg
Randomized, open-label, phase 2a study to evaluate the contribution of artefenomel to the clinical and parasiticidal activity of artefenomel plus ferroquine in African patients with uncomplicated Plasmodium falciparum malaria 2 January 2023 Malar J
Plasmodium vivax in Children: Hidden Burden and Conspicuous Challenges, a Narrative Review 31 December 2022 Infect Dis Ther
A pharmacokinetic-pharmacodynamic model for chemoprotective agents against malaria 31 December 2022 CPT Pharmacometrics Syst Pharmacol
Overexpression of hepatocyte EphA2 enhances liver-stage infection by Plasmodium vivax 12 December 2022 Sci Rep
Safety and efficacy of four drug regimens versus standard-of-care for the treatment of symptomatic outpatients with COVID-19: A randomised, open-label, multi-arm, phase 2 clinical trial 30 November 2022 EBioMedicine
Pregnancy outcomes after first-trimester treatment with artemisinin derivatives versus non-artemisinin antimalarials: a systematic review and individual patient data meta-analysis 25 November 2022 Lancet
'Erythritol', a safe natural sweetener exhibits multi-stage anti-malarial activity by permeating into Plasmodium falciparum through aquaglyceroporin channel. 1 November 2022
Safety, Tolerability, and Parasite Clearance Kinetics in Controlled Human Malaria Infection after Direct Venous Inoculation of Plasmodium falciparum Sporozoites: A Model for Evaluating New Blood-Stage Antimalarial Drugs 11 October 2022 Am J Trop Med Hyg
Discovery and Characterization of Potent, Efficacious, Orally Available Antimalarial Plasmepsin X Inhibitors and Preclinical Safety Assessment of UCB7362 10 October 2022
New in vitro interaction-parasite reduction ratio assay for early derisk in clinical development of antimalarial combinations 5 October 2022
Preliminary Structure-Activity Relationship Study of the MMV Pathogen Box Compound MMV675968 (2,4-Diaminoquinazoline) Unveils Novel Inhibitors of Trypanosoma brucei brucei 4 October 2022 Molecules (Basel, Switzerland)
Exploring a Tetrahydroquinoline Antimalarial Hit from the Medicines for Malaria Pathogen Box and Identification of its Mode of Resistance as PfeEF2 21 September 2022
Tumor distribution by quantitative mass spectrometry imaging of the inhibitor of apoptosis protein antagonist xevinapant in patients with resectable squamous cell carcinoma of the head and neck (EudraCT Number: 2014-004655-31) 13 September 2022 Analytical chemistry
Susceptibilities of Ugandan plasmodium falciparum isolates to proteasome inhibitors 12 September 2022
Plasmodium vivax latent liver infection is characterized by persistent hypnozoites, hypnozoite-derived schizonts, and time-dependent efficacy of primaquine 7 September 2022 Mol Ther Methods Clin Dev
Development of a biomarker to monitor target engagement after treatment with dihydroorotate dehydrogenase inhibitors 31 August 2022 Biochemical pharmacology
Seasonal Malaria Chemoprevention implementation: Effect on malaria incidence and immunity in a context of expansion of P. falciparum resistant genotypes with potential reduction of the effectiveness in sub-Saharan Africa 13 August 2022 Infection and drug resistance
Optimized pyridazinone nutrient channel inhibitors are potent and specific antimalarial leads 7 July 2022 Molecular pharmacology