Artemisinin Forum 2008 - Joint meeting on Ensuring Sustainable Artemisinin Production: Meeting Global Demand

24-26 November 2008
Guilin, China

FORUM AGENDA

Monday 24th Nov 2008

09.30 - 12.30 - Artemisia production- research into aspects of varietal developments, growing techniques and novel methods of artemisinin production
Session Introduction - Malcolm Cutler
Facilitator - Antony Ellman: Artemisinin Production Guide
Xavier Simonnet - Mediplant, Switzerland
Dr Zhong Guo-yue - President, Chongqing Institute of Chinese Medicine
Dr Xiaojun Ma - Director, Guangxi Botanical Garden for Medical Plants
Dr Pham Gia Dien, Director of Technology Center for Pharmaceutical Chemistry and Biochemistry, Vietnamese National Center for Science and Technology
David Clayton - CNAP, York, UK
Charles Giblain - BIONEXX, Madagascar
Colin Hill - Botanical Developments Ltd, UK
Christian Desmarchelier - Fundacion Mundo Sano, Argentina

12.30 - 13.00 - Semi-synthetic artemsinin
Dr Tue Nguyen - OneWorld Health, USA

13.00- 14.30 - Lunch - sponsored by MMV

14.30 - 17.30 - Artemisinin extraction, purification, derivatisation and analysis - research into improved technology aimed at reducing costs, improving efficiency, safety and environmental risk factors
Facilitator - Malcolm Cutler - FSC/MMV
Dr Ge Fahuan - Vice Director, National Engineering Research Centre for Modernisation of Extraction & Separation of TCM and Dr Tian Nan-hui, Beijing Jin Ke Group, China
Duong Ngoc Van - Saokim Pharma, Vietnam
Tong Duy Vinh - Hungtinh Co. Vietnam
Nigel Bremner - Botanical Extracts EPZ, Kenya
Christian Desmarchelier - Fundacion Mundo Sano, Argentina
Dr Bhupinder Khambay - (HFC) Kamtech Technologies / Rothamsted Research, UK
Dr Neil Sullivan - (Ionic Liquids) Bioniqs Ltd, UK and (Analysis) Sensapharm Ltd
Dr Yi Ge - (Polymers) Cranfield University, UK
Colin Hill - (Derivatisation)


Tuesday 25th Nov 2008

08:00 - 09:00 - Registration

09.00 - 09.10 - Opening remarks and Objectives
Malcolm Cutler, Andrea Bosman (WHO), Ian Bathurst (MMV)

09.10 - 09.20 - Welcome and official opening - Ms. Han Jixiu - Deputy Director of International Cooperation, The Ministry of Public Health China

09:20 - 10:00 - Keynote address: "Discovery, development and modern use of artemisinin derivatives for the treatment of malaria", "Overview of current applications of artemisinin derivatives for malaria control"
Dr Ye Zuguang, Chinese Academy of Chinese Medical Sciences, Beijing
Prof. TANG Linhua, Director, National Institute of Parasitic Diseases, Shanghai

10.00 - 10.10 - Conference format, introductions, housekeeping - Malcolm Cutler

10.10 - 10.30 - Tea/coffee break
Facilitator: Malcolm Cutler - FSC/MMV

10.30 - 12.00 - Panel presentations/discussions on Artemisia & artemisinin production experience in China, Vietnam, E. Africa, Madagascar and S.America
Charles Lu - Holley Cotec
Changbai Chen - Chongqing Heng-Star, China
Marc Blanchard, Aremisinin & Farming International
Patrick Henfrey - CEO, Botanical Extracts EPZ, Kenya
Charles Giblain - BIONEXX, Madagascar
Christian Desmarchelier - Fundacion Mundo Sano, Argentina
Colin Hill - Botanical Developments UK

12.00 - 13.00 - Panel presentations/discussions on ACT manufacturers experiences, present needs and future predictions concerning ACT trends, quality and other raw material requirements.
Bjoern Treptow - Novartis Pharma AG, Switzerland
Pradeep Nambia - IPCA, India
ICPA Mission Malaria
Yu Zhemin - Guilin Pharma, China
Emmanuel Katongole - Quality Chemicals, Uganda
Huang Qingyun - Kunming Pharmaceutical Corp

13.00 - 14.00 - Lunch sponsored by IPCA
Facilitator - Anna Wang - MMV

14.00 - 15.00 - Panel presentation/discussion on funds and market dynamics for ACT in the public sector
Ms Thuy Huong Ha - Global Fund
Andrea Bosman - WHO
Lorenzo Witherspoon - UNITAID
Presentations on behalf of UNICEF, USPMI, MSF and World Bank by A. Bosman

15:00 -16.00 - The development of the Affordable Medicines Facility for malaria (AMFm)
Ms Thuy Huong Ha - Global Fund/AMFm

16.00 - 16.20 - Tea/coffee break

16.20- 17.15 - Private sector access initiatives
Anna Wang - MMV
Inder Singh - CHAI
Presentation on behalf of PSI by A. Bosman

17.15 - 18.00 - Panel on ACT/artemisinin market forecasting
Inder Singh - CHAI, Public sector forecast
Presentation of private sector forecast for AMFm on behalf of MIT-Z by A. Bosman
Jacques Pilloy - Artepal - Artemisia/artemisinin needs

Conference Banquet sponsored by Fosun/Guilin Pharma


Wednesday 26th Nov 2008

Facilitator - Ian Bathurst - MMV
8.30 - 9.15 - Artemisinin production and pricing estimates
Jacques Pilloy - Artepal
Malcolm Cutler - MMV

9.15 - 10.00 - Potential mechanisms to secure artemisinin supply
Henk den Besten - IDA Solutions
Inder Singh - CHAI
Jacques Pilloy - Artepal
Malcolm Cutler - FSC/MMV

10.00 - 10.30 - Tea/Coffee break

10.30 - 11.00 - Report of the outcome of the 2008 Artemisinin Enterprise Conference, New technologies for artemisinin production and alternatives to artemisinin.
David Clayton - CNAP, University of York, representative of the Artemisinin Enterprise

11.00 - 11.30 - Synthetic therapies for the treatment of malaria
Jörg Möhrle - MMV

11.30 - 12.00 - Reporting of observations and recommendations from technical meetings:
1) Artemisia production
2) Artemisinin extraction, derivatisation and analysis

Presentations by facilitators of the technical meetings:
Antony Ellman
Malcolm Cutler

12.00 - 12.30 - Expansion / company presentation

12:30 - 14.00 - Lunch - sponsored by Holley - Cotec
Facilitator - Andrea Bosman - WHO

14.00 - 15.00 - Quality requirements for artemisinin production facilities. GMP for API and ACT manufacture
Maryam Mehmandoust - WHO
Valérie Faillot-Proux - Sanofi Aventis

15.00 - 16.00 - Pharmaceutical standards for artemisinin and its derivatives. Requirements for pre-qualification of ACTs
Maryam Mehmandoust - WHO
Jacque Pilloy - Artepal
Andrew Bosman - Quality Assurance of Anti-Malarial Medicines

16.00 - 16.30 - Tea/coffee break
Facilitator - Ian Boulton

16:30 -17.30 - Visions for the future
Presentation of key findings/message for sustainable development of artemisinin supply
Facilitators of the main sessions:
Malcolm Cutler
Anthony Ellman
Anna Wang
Ian Bathurst
Andrea Bosman

17.30 - Closure of the meeting