Quantitative Systems Pharmacology (QSP) is a new emerging area of science. It brings a systems approach to the development of pharmaceuticals, using quantitative approaches such as mathematical modelling and data analysis to integrate sub-cellular genetic and protein-protein interaction networks with body scale information and clinical data.
For pharmaceutical development this means the advantage of traditional pharmacokinetic pharmacodynamic (PKPD) modelling approaches, often used in clinical trial design, to the earlier stages of drug development. To realise its goal the field requires input from many different areas of science including pharmacology, cell and molecular biology, mathematics and statistics.
The UK QSP Network was formed by an enthusiastic group of UK and international scientists in industry and academia, to bring and nurture this new emerging area of science to the UK research space.
Meeting participants will spend 5 days tackling QSP problems brought by industrial and academic clinical pharmacologists, life, biological and biomedical scientists focused around QSP. The workshop will follow a similar format to the internationally recognised Mathematics in Medicine Study Groups.
MMV's Mohammed Cherkaoui and Nicole Andenmatten will be presenting a problem on the following topic:
A liver model for chemoprotection against malaria