MMV's pipeline of antimalarial drugs

Download the MMV-supported projects slide and the global portfolio of antimalarial medicines slide.

Detailed information is available for translational, development and access projects (click on the boxes below).

MMV's pipeline of antimalarial drugs

Research
4-aminoquinoline
LSTM and University of Liverpool
Lead optimization
Phenotypic projects
UNICAMP/USP
Lead optimization
KRS
DDU Dundee/Eisai
Lead optimization
MMV654
Calibr
Candidate profiling
PRS
Takeda
Lead optimization
MMV072
Eisai
Candidate profiling
Miniportfolio
Novartis
Lead optimization
Molecular Target
Mitsubishi Tanabe
Lead optimization
Molecular target
Merck KGaA-UCT
Lead optimization
YRS
Takeda
Lead optimization
Pf Carl series
Calibr
Lead optimization
Irresistibles
GHDDI
Lead optimization
GWT1
Eisai
Lead optimization
DHODH
Broad
Lead optimization
DHODH
UTSW/UW/Monash
Lead optimization
ATP4 series Drexel
Drexel
Lead optimization
Access
View project
Sulfadoxine-pyrimethamine
Universal Corporation
Prevention for pregnant women and infants
Approved
View project
Tafenoquine paediatric
GSK
Prevention of relapse
Approved
View project
Artesunate for injection
Ipca
Severe malaria
Approved
View project
Sulfadoxine- pyrimethamine+ amodiaquine dispersible
S Kant
Chemoprevention for children
Approved
View project
Artemether-lumefantrine dispersible
Novartis
Uncomplicated malaria
Approved
View project
Artesunate rectal capsules
Strides Pharma
Pre-referral intervention
Approved
View project
Tafenoquine
GSK
Prevention of relapse
Approved
View project
Dihydroartemisinin-piperaquine
Alfasigma
Uncomplicated malaria
Approved
View project
Artesunate- mefloquine
Cipla
Uncomplicated malaria
Approved
View project
Artesunate rectal capsules
Cipla
Pre-referral intervention
Approved
View project
Pyronaridine-artesunate granules
Shin Poong
Uncomplicated malaria
Approved
View project
Sulfadoxine- pyrimethamine+ amodiaquine dispersible
Fosun Pharma
Chemoprevention for children
Approved
View project
Pyronaridine- artesunate
Shin Poong
Uncomplicated malaria
Approved
View project
Artesunate- amodiaquine
Sanofi
Uncomplicated malaria
Approved
View project
Artesunate for injection
Fosun Pharma
Severe malaria
Approved
Product development
View project
ZY19489+ ferroquine
Zydus
Patient exploratory
View project
Sulfadoxine-pyrimethamine
Swipha/Biogaran
Regulatory review
View project
Sulfadoxine-pyrimethamine
Emzor Pharmaceutical
Regulatory review
View project
Primaquine dispersible
B&O Pharm
Patient confirmatory
View project
Cipargamin
Novartis
Patient exploratory
View project
M5717+pyronaridine
Merck KGaA/Shin Poong
Patient exploratory
View project
Artemether-lumefantrine
Novartis
Patient confirmatory
View project
Ganaplacide-lumefantrine
Novartis
Patient exploratory
View project
Dihydroartemisinin- piperaquine dispersible
Alfasigma
Patient confirmatory
View project
Artemether-lumefantrine-amodiaquine FDC
Tridem/MORU
Patient confirmatory
Translational
View project
MMV167
(OHSU USF)
Preclinical
View project
MMV609
University of Kentucky
Preclinical
View project
MMV183
TropIQ
Preclinical
View project
Atoguanil
Ipca
Human volunteers
View project
GSK701
GSK
Human volunteers
View project
IWY357
Novartis
Preclinical
View project
GSK484
GSK
Preclinical
View project
MMV371
Janssen
Preclinical
View project
Piperaquine + pyronaridine
Shin Poong
Human volunteers
View project
INE963
Novartis
Human volunteers
View project
MMV533
(Sanofi)
Human volunteers