400 diverse drug-like molecules active against bacteria, viruses or fungi; available free of charge
In response, MMV and DNDi, in association with scientists from industry and academia, have assembled the Pandemic Response Box to foster new research into treatments for pandemic diseases. The box will provide the community with a set of 400 structurally diverse compounds for screening against infective and neglected diseases. These 400 compounds with diverse mechanisms of action have been selected by disease experts from a comprehensive list of antibacterial, antivirals or antifungal compounds. All of them are either already marketed or are in various phases of drug discovery or development. The compounds biological activity has not been confirmed by MMV/DNDi partners, the selection has been made based on the information available in the literature.
The Pandemic Response Box is composed of 201 antibacterials, 153 antivirals and 46 antifungals.