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  • ICH

    International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use, which issues guidelines for good laboratory and clinical practice. 7

  • Immunity

    Protection generated by the body’s immune system, in response to previous malaria attacks, resulting in ability to control or lessen a malaria attack.1

  • in silico

    modeling research conducted by means of computer simulation.3

  • in vitro

    (of processes or reactions) taking place in a test tube, culture dish or elsewhere outside a living organism.4

  • in vivo

    (of processes) taking place in a living organism.4

  • Incubation period

    The interval of time between infection by a microorganism and the onset of the illness or the first symptoms of the illness. In malaria, the incubation is between the mosquito bite and the first symptoms. Incubation periods range from 7 to 40 days, depending on species.1

  • Intermittent preventive treatment

    Intermittent preventive treatment (IPT) describes the administration of an antimalarial drug or drug combination at specified times, often corresponding to the time when a subject has access to health services, to individuals at risk, whether or not they are infected. It is accepted that blood concentrations will fall below inhibitory concentrations between drug administrations.6

  • Investigational new drug (IND)

    A new drug, antibiotic drug, or biological drug that is used in a clinical investigation. It also includes a biological product used in vitro for diagnostic purposes. 5