Aline Fuchs

PKPD Translational Medicine Scientist
Research & Development

What I do at MMV:

My role is to develop and apply pharmacometric models to help understanding the behaviour of compounds as a single drug as well as how the compounds interact in combination. I contribute to the interpretation of in vitro data, the translation from preclinical to clinical, dose selection for clinical studies and combination of drugs via PK/PD modeling and simulation.

Why I work at MMV:

I have a strong interest in infectious diseases and PK/PD has a crucial role in the development of new drugs and drug combinations. I find it motivating to apply my knowledge to tackling the specific challenges that low and middle-income countries are facing in a context of increasing drug resistance globally. MMV provides an exciting environment to succeed in the challenging task of developing antimalarials via innovative approaches and collaborations. I feel privileged to contribute to filling the gap of unmet needs for a disease of poverty such as malaria.

More about me:

I am trained in both pharmacology and pharmacometrics. After completing my studies in pharmacy with a specialization in pharmacokinetics, I obtained my PhD from the University Hospital of Lausanne in 2015 with a focus on therapeutic drug monitoring assisted by modeling & simulations and drug modeling in infectious diseases. Following this, I joined the Paediatric Pharmacology Group at Basel University Children’s hospital where my research focused on antibiotic dosing and antibiotic stewardship of neonates and children using pharmacometric approaches. During these years I also served as a clinical pharmacology consultant in the group.

Ask me about:

Pharmacokinetics/pharmacodynamics, modeling & simulation, pharmacology and infectious diseases. Aside from science, join me  for a swim or a good concert.